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NGF and other substances important to pain signalling are useful biomarkers to measure pain Goto et al 2016. Asperger syndrome AS also known as Aspergers refers to a sub-category of the autism spectrum that is no longer an official diagnosis in the United States as of 2013 having been merged into autism spectrum disorder ASD.

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It is a neurodevelopmental disorder characterized by significant difficulties in social interaction and nonverbal communication along with.

. Low back pain LBP is the most common musculoskeletal problem globally 1-4It is the leading cause of activity limitation and absenteeism from work 5-7 and results in a huge medical burden and economic cost 28It is consequently one of the major global public health problems 9-11The Global Burden of Disease GBD Study is updated. Auto-antibodies antibodies that act against the self are involved in a variety of pain states such as rheumatoid arthritis Guillain-Barré syndrome and complex regional pain syndrome McMahon et al 2015.

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Complex Regional Pain Syndrome

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Mechanism Specific Rehabilitation Management Of Complex Regional Pain Syndrome Proposed Recommendations From Evidence Synthesis Journal Of Hand Therapy